Moderna COVID-19 Vax Produced Immune Responses for 4 Months

Antibody responses to Moderna’s COVID-19 vaccine candidate, mRNA-1273, remained strong for almost 4 months following vaccination, data from a phase I trial indicated.

Serum neutralizing antibodies were detected in 34 healthy adult volunteers at day 119 following the first dose, and 90 days following the second dose, reported Alicia Widge, MD, of the National Institute of Allergy and Infectious Diseases (NIAID) in Bethesda, Maryland, and colleagues.

Moreover, both binding and neutralizing geometric mean titers exceeded those in 41 healthy controls who were recovering from COVID-19, the authors wrote in a Correspondence piece in the New England Journal of Medicine.

“Although correlates of protection against SARS-CoV-2 infection in humans are not yet established, these results show […] mRNA-1273 has the potential to provide durable humoral immunity,” the researchers wrote.

Importantly, they also found no new adverse events considered to be related to the vaccine after day 57.

Moderna recently made

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Strong immune response found in asymptomatic patients; virus crosses throat membrane into brain

a close up of a flower: FILE PHOTO: A computer image created by Nexu Science Communication together with Trinity College in Dublin, shows a model structurally representative of a betacoronavirus which is the type of virus linked to COVID-19

© Reuters/Social Media
FILE PHOTO: A computer image created by Nexu Science Communication together with Trinity College in Dublin, shows a model structurally representative of a betacoronavirus which is the type of virus linked to COVID-19

By Nancy Lapid

(Reuters) – The following is a roundup of some of the latest scientific studies on the novel coronavirus and efforts to find treatments and vaccines for COVID-19, the illness caused by the virus.

Immune system responds strongly in asymptomatic COVID-19

Asymptomatic people infected with COVID-19 are mounting robust immune responses that differ from responses in those who become ill, according to a study that appears to contradict previous thinking by health experts. Researchers studied immune system T cells in 76 symptomatic COVID-19 patients and 85 infected individuals without symptoms and reported their findings on Friday on bioRxiv ahead of peer review. Some of these cells – CD8+ T cells – can

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Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer’s disease

Study cohort characteristics

Our meta-analysis included 1030 prefrontal cortex brain samples from four independent cohorts (Table 1), previously described in the ROSMAP14, Mt. Sinai15, London8, and Gasparoni16 methylation studies. To assess the diagnostic utility of DNA methylation as clinical biomarkers, we also compared methylation differences in brain samples with premortem whole blood samples from a subset of subjects in the London cohort. Among the four cohorts, the mean age at death ranged from 73.6 years to 86.3 years, and the percentage of females ranged from 51.8 to 63.5%.

Table 1 Sample characteristics of the brain and blood cohorts included in the meta-analysis.

Meta-analysis identified methylation differences significantly associated with AD Braak stage at individual CpGs and co-methylated genomic regions

Adjusting for estimated cell-type proportions (i.e., the proportion of neurons), age at death, sex, and batch effects, our meta-analysis of single CpGs in the

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Gut immune cells may play key role in MS

Gut immune cells appear to help dampen multiple sclerosis flare-ups, researchers say.

Such flare-ups — which can cause vision loss, memory problems, pain and other symptoms — often subside on their own after days or weeks, but it’s not clear what triggers multiple sclerosis patients to go from remission to flare-up and back again.

An international team of researchers recently found that in animal models of MS, gut immune cells leave the digestive system and travel to the brain and seem to reduce inflammation there.

“It was a very new idea,” team member Sergio Baranzini, professor of neurology at the University of California, San Francisco, said in a university news release. “Nobody thought to look for this type of immune cell.”

In the new study, Baranzini and his colleagues analyzed cerebrospinal fluid from MS patients for an antibody called IgA, which is expressed by gut immune cells.

The investigators discovered

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Proper nutrition can boost your immune system

A dietary defense against disease
Eating fruits and vegetables in a rainbow of colors is a good way to obtain vital nutrients. Credit: Jean Beaufort /

The holiday season is here, but unfortunately, so is the second wave of COVID-19 cases. As the days get cooler and wetter and the flu begins to circulate again, coronavirus prevention efforts—such as social distancing and wearing face coverings—are more important than ever.

Thankfully, an effective vaccine appears to be on the horizon. But until then, what else can we do to safeguard ourselves from infection? There is now ample evidence suggesting that critical COVID-19 cases are usually linked to such concurrent factors as obesity, diabetes, hypertension or heart disease—chronic conditions often related to poor diet. Furthermore, a balanced diet supplies the body with a range of macro- and micronutrients that prime the immune system to prevent or fight disease. Proper nutrition could help us at least avoid

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Q-ION Immune Defense Reviews – Does this Supplement Really Work? Must Read

Press release content from TS Newswire. The AP news staff was not involved in its creation.

New York, NY ( TS Newswire ) — 08 Nov 2020

Q-ION Immune Defense is a doctor-approved supplement that quickly strengthens and protects your immune system. This product works effectively as an immune defense formula that protects yourself from airborne pathogens, microbes, and infections.

This Q-Ion immune defense is fast becoming the most trusted supplement that improves the bodys immune response to keep your infections away. This product is made with state-of-the-art Ion blast technology that helps block the entry of pathogens by boosting anti-bodies in ramping up your natural immune defense.

It strengthens your immune system as a key the defending the body against potential pathogens that are specifically developed and designed Q-Ion with a unique blend of natural ingredients. It boosts your immune system and offers you that

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